| Round 1 | Round 2 | Round 3 | Round 4 |
|---|---|---|---|
| HSV Troisdorf (Herren) | |||
30. September 2021  26-19  | |||
| HSV Troisdorf (Herren) | |||
19. September 2021 20:00  | |||
| Godesberger TV | |||
| TSV Bonn rrh. | |||
30. September 2021 00:00 | |||
| TSV Bonn rrh. | |||
| SG Ollheim-Straßfeld | |||
29. September 2021  33-27  | |||
| TuS Chlodwig Zülpich | |||
17. November 2021 28-29  | |||
| TuS Chlodwig Zülpich | |||
| TV Rheinbach | |||
| TV Rheinbach | |||
30. September 2021 00:00 | |||
| TV Rheinbach | |||
| VfB Schleiden | |||
30. September 2021  32-19  | |||
| VfB Schleiden | |||
vs  | |||
| Poppelsdorfer HV | |||
| SV Rot-Weiss Merl | |||
5. Oktober 2021 30-21  | |||
| SV Rot-Weiss Merl | |||
| TuS Niederpleis | |||
| TV Palmersheim | |||
29. September 2021  00:00 | |||
| TV Palmersheim | |||
vs  | |||
| HSG Sieg | |||
30. September 2021  29-31 | |||
| HSG Euskirchen | |||
| HSG Euskirchen |